Early life imprints the hierarchy of T cell clone sizes

The adaptive immune system responds to pathogens by selecting clones of cells with specific receptors.While clonal selection in response to particular antigens has g35 coupe fender been studied in detail, it is unknown how a lifetime of exposures to many antigens collectively shape the immune repertoire.Here, using mathematical modeling and statist

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Y-Chromosome haplogroup I prehistoric gene flow in Europe

To investigate which aspects of contemporary human Y-chromosome variation in Europe are characteristic 100w products of primary colonization, late-glacial expansions from refuge areas, Neolithic dispersals or more recent events in gene flow haplogroup I was analyzed.The analysis of Hg I Y chromosomes revealed several sub-clades with distinct geogra

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Coordinated Roll Control of Conformal Finless Flying Wing Aircraft

Attitude control of tailless aircraft is typically achieved through a system of trailing-edge flaps that produce coupled control 15-eg2373cl effects in pitch, roll and yaw due to changes in lift and drag distributions.This paper presents a novel control allocation method which allows conformal trailing-edge controls to generate yawing moments with

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